TTP

TTP (Thrombotic thrombocytopenic purpura), also called Moschcowitz syndrome, was first described in 1924.

It is a rare, life-threatening, disorder of the blood-coagulation system. It can cause thrombosis especially in the brain and in the kidneys.

Symptoms:

• thrombocytopenia (bleeding tendency)
• haemolytic anaemia
• neurological symptoms (e.g. stroke, about 65%)

• infections
• drugs (e.g. Mitomycin C^[1])
• tumours

For further information please visit the website of the TTP support group.
http://www.ttpforum.de/

Note:

• [1] Mitomicin C is a common cytostatic drug. It is widely used in the chemotherapy of many types of cancer, such as bladder, stomach, bowel, lung and breast cancer. TTP is listed as a "rare, but dangerous" side effect. Around 10% of the patients treated with MMC develop TTP during the first 5-10 months after the start of therapy (Dr. Hans-Peter Lipp in "Im Focus Onkologie" 5-2007).